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Friday September 24

 

 

8:30-10:30   | Workshop 8

Dysfunction of glial cells in neuronal pathologies
• Alexander Mongin (Albany, USA)
   PURINERGIC REGULATION OF MICROGLIAL MOTILITY, ION TRANSPORT,
   AND NEUROTRANSMITTER RELEASE

  • Sandra J. Hewett (Farmington, USA)
    THE JANUS FACED EFFECTS OF ASTROCYTE IL-1 SIGNALING: SYSTEM XC AT THE CROSSROADS OF PROTECTION AND INJURY
  • Reza Khorooshi (Odense, Denmark)
    IMMUNE-GLIAL INTERACTIONS IN RESPONSE TO INFLAMMATION AND INJURY
  • Serge Rivest (Québec, Canada)
    BONE MARROW STEM CELLS TO THE RESCUE OF BRAIN DISEASES
  • Lyanne C. Schlichter (Toronto, Canada)
    INFLAMMATION AND ACUTE CNS INJURY

8:30-10:30 | Symposium 9

Novel animal models and genetic modification techniques in the rat

  • Aron M. Geurts (Milwaukee, USA)
    FROM GENETICS TO FUNCTION FOR HUMAN DISEASE USING TRANSGENIC RESCUE AND GENE KO IN SENSITIZED RAT STRAINS
  • Michal Pravenec (Prague, Czech Republic)
    NOVEL TOOLS FOR GENETIC ANALYSES OF COMPLEX TRAITS IN THE SPONTANEOUSLY HYPERTENSIVE RAT
  • Tomoji Mashimo (Kyoto, Japan)
    RECENT PROGRESS OF GENE-TARGETING TECHNOLOGIES IN RATS: ENU  MUTAGENESIS AND ZINC FINGER NUCLEASES
  • Nataliya Krupina (Moscow, Russia), Nadezhda Khlebnikova, Ekaterina Kushnareva
    IS INCREASE IN PROLYL ENDOPEPTIDASE AND DIPEPTIDYL PEPTIDASE IV ACTIVITIES IN BRAIN STRUCTURES: A NEW MECHANISM OF DEPRESSION AND ANXIETY?
  • Takahiro Ueno (Tokyo, Japan), Noboru Fukuda, Kazunobu Tahira, Taro Matsumoto, Masayoshi Soma, Katsumi Ikeda, Junko Yamamoto, Yukio Yamori
    DYSLIPIDEMIA AND ALTERED HEPATIC GENE EXPRESSION IN A NEW RAT METABOLIC SYNDROME MODEL (SHRSP. ZLeprfa IsmDprc)

8:30-10:30 | Symposium 10

Novel pathophysiological approaches and tools: From genes to Systems biology and signal transduction

  • Chenjiang Ying (Wuhan, China), Weijie Yi, Hiroaki Aso, Takanori Noguchi, Chong Tian, Katsumi Ikeda, Yukio Yamori, Yasuo Nara
    THE DIFFERENCES BETWEEN SHR AND SHRSP: FROM PROTEOMIC TO FUNCTIONAL ANALYSIS
  • Hiroyuki Matsuda (Montréal, Canada), Suzanne Cossette, Catherine Michel, Junzheng Peng, Julie L. Lavoie, Sergei Orlov, Pavel Hamet, Johanne Tremblay
    THE HYPERTENSION-RELATED, CALCIUM-REGULATED GENE (HCARG) ACCELERATES THE REGENERATION OF RENAL TUBULAR EPITHELIAL CELLS AFTER ACUTE RENAL INJURY
  • Henry Aceros (Montréal, Canada), Safia Terki, Georges Farah, Nicolas Noiseux, Suhayla Mukaddam-Daher
    IMPROVED CARDIAC STRUCTURE AND PERFORMANCE BY MOXONIDINE IN SHR INVOLVES DIRECT ANTI-APOPTOTIC ACTIONS ON CARDIAC IMIDAZOLINE RECEPTORS
  • Yukio Yamori (Nishinomiya, Japan), Mari Mori, Miki Sagara, Chizuru Onishi, Kiyotomi Imai
    ALLEVIATION OF SALT-SENSITIVITY BY SOY AND FISH INTAKES IN HUMANS AND SHRSP
  • Allen W. Cowley (Milwaukee, USA)
    UNRAVELING THE GENOMIC BASIS OF HYPERTENSION: RAT MODEL SYSTEMS
  • Benoît Coulombe (Montréal, Canada)
    MAPPING THE DISEASE PROTEIN INTERACTOME: TOWARDS A MOLECULAR MEDICINE GPS TO ACCELERATE DRUG AND BIOMARKER DISCOVERY
10:30-11:00 | Coffee break 11:00-12:00 | Plenary Session 5
Diseasome
• Albert Barabasi (Boston, USA)
NETWORK MEDICINE: FROM CELLULAR NETWORKS TO THE HUMAN DISEASOME

12:00-14:00 | Lunch Symposium sponsored by Novartis Japan

Current Topics on BP Management

• Chair: Prof. Kazuaki Shimamoto (Sapporo, Japan)

  • Speakers:
    Prof. Noboru Fukuda     (Tokyo, Japan)
    STEM CELLS, OXIDATIVE STRESS AND NEW TREATMENT STRATEGIES FOR CARDIOVASCULAR AND RENAL DISEASES
    Prof. Peter P. Liu (Toronto, Canada)
    ADVANCING THE FRONTIERS OF BP CONTROL - WE CAN ASPIRE HIGHER
14:00-15:45 | Symposium 11

Genetics and Metabonomics of cardiometabolic diseases

  • Norbert Hübner (Berlin, Germany)
    CONSERVED GENETIC REGULATION OF CO-EXPRESSION NETWORKS IN THE  RAT AND HUMANS AND ITS IMPLICATION FOR CARDIOMETABOLIC DISEASE
  • Norihiro Kato (Tokyo, Japan)
    GENOME-WIDE EXPLORATION OF GENETIC SUSCEPTIBILITY TO CARDIOMETABOLIC DISEASES
  • Tomohiro Katsuya (Suita, Japan), Kei Asayama, Takayoshi Ohkubo, Ken Sugimoto, Ryusuke Inoue, Hirohito Metoki, Kei Kamide, Taku Obara, Mitsuru Ohishi, Ryuichi Morishita, Toshio Ogihara, Yutaka Imai, Hiromi Rakugi
    GENOME-WIDE PHARMACOGENOMIC RESPONSE TO ANTIHYPERTENSIVE MEDICATION: THE HOMED-BP-GENE STUDY
  • František Liska (Prague, Czech Republic), Michaela Krupková, Michaela Jankù, Drahomíra Køenová, Ondřej Šeda, Michal Pravenec, Vladimír Køen
    THE POSSIBLE ROLE OF PROMYELOCYTIC LEUKEMIA ZINC FINGER (PLZF) IN THE PATHOGENESIS OF HYPERTENSION AND CARDIAC HYPERTROPHY IN SHR
  • Francine Marques (Sydney, Australia), Anna Campain, Jean Yang, Brian Morris
    TRANSCRIPTOMICS OF RAT GENETIC HYPERTENSION: A META-ANALYSIS
14:00-15:45 | Symposium 12

Therapeutic targets (sponsored by CIHR ICRH)

  • Li Kun (Shanghai, China), Chen Chang-Jie, Yong-Yu Li, Gu Yong, Lin Shanyan
    ACID LOADING INDUCE RAT GLOMERULAR MESANGIAL CELLS PROLIFERATION BY ACTIVATION OF NA+-H+ EXCHANGER 1 ACTIVITY
  • Sveltana Koltsova (Montréal, Canada), Georgy Maximov, Julie L. Lavoie, Sergei Kotelevtsev, Johanne Tremblay, Ryszard Grygorczyk, Pavel Hamet, Sergei Orlov
    MYOGENIC TONE IN MESENTERIC ARTERIES INVOLVES P2Y RECEPTOR-MEDIATED, NKCC1-DEPENDENT SIGNALING
  • Yong Jiang (Guangzhou, China), Zhifeng Liu, Juan Wang, Jinghua Liu, Jia Xu, Peng Deng
    ROLE OF TSHMG IN THE REGULATION OF INOS GENE EXPRESSION IN THE LIVERS OF MICE WITH ENDOTOXIC SHOCK
  • Pavel Hamet (Montreal, Canada)
    COMING SOON
  • Peter Liu (Toronto, Canada)
    IDENTIFYING NOVEL PATHOPHYSIOLOGY AND THERAPEUTIC TARGETS IN RODENT MODELS OF HUMAN DISEASE - EXAMPLES USING HEART FAILURE
14:00-15:45 | Symposium 13

Genomics, epigenomics and pharmacogenomics of hypertension and cardiovascular diseases

  • Jaroslav Kuneš (Prague, Czech Republic)
    EARLY LIFE ENVIRONMENTAL IMPACT ON HYPERTENSION DEVELOPMENT
  • Yoram Yagil (Ashkelon, Israel)
    SEXUAL DIMORPHISM IN COMPLEX DISEASES
  • Jacques Turgeon (Montréal, Canada)
    PHARMACOGENETICS OF CARDIOVASCULAR DRUGS
  • Betty Nabatanzi (Mukono, Uganda), Richard Lule, Lawrence Luzinda
    AN EXAMINATION OF THE COMBINED EFFECTS OF MATERNAL CHARACTERISTICS, ENVIRONMENT AND TREATMENT PROGRAMS ON THE PREVALENCE OF DIARRHEA AMONGST INFANTS AND CHILDREN IN UGANDA
15:45-16:15 | Coffee break

15:45-18:00 | Poster Session D : Cardiovascular, hypertension and
                       animal models

19:30            | President's Dinner (sponsored by Genome Québec)
                       (on invitation only)